Login
Search

Biography not available yet.

Events

crowd of people sitting on chairs inside room
23
Apr
2026
Seminar
Past
External
Huntingtin as a Regulator of Actin Architecture: Insights from Developing Cortical Circuits
Mariacristina Capizzi

Abstract Huntington’s disease (HD) is a monogenic neurodegenerative disorder caused by a CAG expansion in the HTT gene. The work […]

Amphi Hermann (1st floor), Faculté de Médecine Lyon-Est Rockefeller
crowd of people sitting on chairs inside room
07
Nov
2023
Seminar
Past
External
Selective autophagy of phase-separated p62: from molecular mechanism to pathophysiology
Pr Masaaki Komatsu
Médiathèque Paul Zech

News

06
Jul
2026
Announcement
Many thanks to Natacha Triou for inviting us to Radio France!

Many thanks to Natacha Triou for inviting us to Radio France! Autophagy was recently featured on the program La Science, CQFD broadcast on France […]

Projects

Type:
Category:
Project
Fundamental
National
Better characterize the beneficial role of a variant of the autophagic receptor NDP52 in the context of Alzheimer’s disease
Principal investigator Flavie Strappazzon
Team: Autophagy in pathophysiology
View project
Project
Fundamental
National
Investigate the importance of mitophagy in the context of neurodevelopment
Principal investigator Flavie Strappazzon
Principal investigator Julien Courchet
Team: Autophagy in pathophysiology, Energy metabolism and neuronal development
View project
Project
Fundamental
National
Autophagy/mitophagy regulation in striated skeletal muscle and in the context of Myotonic Dystrophy type 1
Principal investigator Flavie Strappazzon
Team: Autophagy in pathophysiology
View project

Publications

2026
Bruqi K, Strappazzon F, Autophagy and selective autophagy receptors: Key players against Alzheimer’s disease., Neural Regen Res 2026 Oct; 21(10): 4785-4797.
2026
Carpentier M, Chatron N, Rouvet I, Monin P, Nadaud B, Consortium A, Sanlaville D, Courchet J, Strapp..., A fetus with severe developmental defects caused by dominant-negative and hypomorphic ATG7 alleles., Autophagy 2026 Sep; 22(9): 2232-2247.
2026
Pellegrini FR, Iuzzolino A, De Palma C, Ambrosio F, Fianco G, Naso FD, Paone A, Rinaldo S, Cutruzzol..., α-tubulin N-acetyltransferase 1 regulates NCOA4-mediated ferritinophagy and protects cancer cells from ferroptosis., Cell Mol Biol Lett 2026 Jun; 31(1): .
2026
Naso FD, Stagni V, Strappazzon F, Protocols for MCF-7 derived mammosphere generation and anti-cancer drug testing., Methods Cell Biol 2026 ; 206(): 145-154.
2025
Bruqi K, Strappazzon F, NDP52 and its emerging role in pathogenesis., Cell Death Dis 2025 May; 16(1): 359.
2025
Mattioni A, Carsetti C, Bruqi K, Caputo V, Cianfanelli V, Bacalini MG, Casa M, Gabelli C, Giardina E..., A variant of the autophagic receptor NDP52 counteracts phospho-TAU accumulation and emerges as a protective factor for Alzheimer’s disease., Cell Death Dis 2025 Apr; 16(1): 300.
2024
Anna Mattioni, Claudia Carsetti, Krenare Bruqi, Valerio Caputo, Valentina Cianfanelli, Maria Giulia ..., A variant of the autophagic receptor NDP52 counteracts phospho-TAU accumulation and emerges as a protective factor for Alzheimer Disease Une variante du récepteur autophagique NDP52 contrecarre l’accumulation de phospho-TAU et apparaît comme un facteur de protection contre la maladie d’Alzheimer, .
2024
Naso FD, Bruqi K, Manzini V, Chiurchiù V, D'Onofrio M, Arisi I, Strappazzon F, miR-218-5p and doxorubicin combination enhances anticancer activity in breast cancer cells through Parkin-dependent mitophagy inhibition., Cell Death Discov 2024 Mar; 10(1): 149.
2024
Francesco Davide Naso, Flavie Strappazzon, Combining doxorubicin and miR-218-5p: a new strategy to fight breast cancer?, Autophagy Reports.
2023
Fiorella Faienza, Federica Polverino, Girish Rajendraprasad, Giacomo Milletti, Zehan Hu, Barbara Col..., AMBRA1 phosphorylation by CDK1 and PLK1 regulates mitotic spindle orientation, Cellular and Molecular Life Sciences.
2023
Ilio Vitale, Federico Pietrocola, Emma Guilbaud, Stuart Aaronson, John Abrams, Dieter Adam, Massimil..., Apoptotic cell death in disease—Current understanding of the NCCD 2023, Cell Death and Differentiation.
2023
Flavie Strappazzon, Habilitation à Diriger des Recherches L’autophagie sélective au coeur de la physiopathologie, .
2022
Alfonso Schiavi, Alessandra Runci, Teresa Maiorino, Francesco Davide Naso, Marta Barenys, Ellen Frit..., Cobalt chloride has beneficial effects across species through a hormetic mechanism, Frontiers in Cell and Developmental Biology.
2022
Gambarotto L, Metti S, Chrisam M, Cerqua C, Sabatelli P, Armani A, Zanon C, Spizzotin M, Castagnaro ..., Ambra1 deficiency impairs mitophagy in skeletal muscle., J Cachexia Sarcopenia Muscle 2022 Aug; 13(4): 2211-2224.
2021
Di Rita A, Angelini DF, Maiorino T, Caputo V, Cascella R, Kumar M, Tiberti M, Lambrughi M, Wesch N, ..., Characterization of a natural variant of human NDP52 and its functional consequences on mitophagy., Cell Death Differ 2021 Aug; 28(8): 2499-2516.
2021
Di Rita A, Strappazzon F, A protective variant of the autophagy receptor CALCOCO2/NDP52 in Multiple Sclerosis (MS)., Autophagy 2021 Jun; 17(6): 1565-1567.
2021
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard M..., Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1., Autophagy 2021 Jan; 17(1): 1-382.