Charlène Magnani

About

Originally from northern Burgundy, and driven by a desire for independence, I chose a short and practical academic path, earning a professional Bachelor’s degree. I began my career as a lab technician in 2006 at Diaclone in Besançon, where I spent eight years developing monoclonal antibodies and ELISA kits.

Motivated by a need for new scientific challenges, I then moved into academic research. I first worked for four years in an INSERM team in Dijon, studying cholesterol metabolism using a mouse model. In 2018, I joined the NeuroMyogene Institute in Lyon.

Here, my work focuses on understanding how certain proteins contribute to nuclear reorganization in response to DNA damage. To explore these mechanisms, I use advanced cellular tools such as stem cell differentiation into motor neurons, along with high-resolution imaging techniques like immunofluorescence, RNA FISH, and proximity ligation assay.

A true “Swiss army knife” in the lab, I value versatility, curiosity, and teamwork.

Whenever I can, I escape to the mountains. Depending on the season, you’ll find me with a bivouac tent on my back, ski touring gear on my feet, or a climbing harness and rope in my pack—always eager to discover what lies beyond the next summit.