Publications 2022

 

Pharmacological inhibition of HDAC6 improves muscle phenotypes in dystrophin-deficient mice by downregulating TGF-β via Smad3 acetylation.

A. Osseni, A. Ravel-Chapuis, E. Belotti, I. Scionti, Y-G. Gangloff, V. Moncollin, L. Mazelin, R. Mounier, P. Leblanc, B. J. Jasmin & L. Schaeffer.

Nature Communications 13, Article number: 7108 (2022)

Repurposing pentamidine using hyaluronic acid-based nanocarriers for skeletal muscle treatment in myotonic dystrophy.

Repellin M., Carton F., Boschi F., Galiè M., Perduca M., Calderan L., Jacquier A., Carras J., Schaeffer L., Briançon S., Lollo G., Malatesta M.

Nanomedicine: Nanotechnology, Biology and Medicine Volume 47, January 2023, 102623

Cardiorespiratory Fitness and Neuromuscular Function of Mechanically Ventilated ICU COVID-19 Patients.

Millet GY, Kennouche D, Foschia C, Brownstein CG, Gondin J, Lapole T, Rimaud D, Royer N, Thiery G, Gauthier V, Oujamaa L, Sorg M, Vergès S, Doutreleau S, Marillier M, Prudent M, Bitker L, Féasson L, Gergelé L, Stauffer E, Guichon C, Morel J.

Crit Care Med 2022 Nov 1;50(11):1555-1565

Role of macrophages during skeletal muscle regeneration and hypertrophy-Implications for immunomodulatory strategies.

Bernard C, Zavoriti A, Pucelle Q, Chazaud B, Gondin J.

Physiol Rep 2022 Oct;10(19):e15480

JMJD3 activated hyaluronan synthesis drives muscle regeneration in an inflammatory environment.

Nakka K, Hachmer S, Mokhtari Z, Kovac R, Bandukwala H, Bernard C, Li Y, Xie G, Liu C, Fallahi M, Megeney LA, Gondin J, Chazaud B, Brand M, Zha X, Ge K, Dilworth FJ.

Science 2022 Aug 5;377(6606):666-669

Monocyte Phenotypes and Physical Activity in Patients with Carotid Atherosclerosis.

Mura M, Weiss-Gayet M, Della-Schiava N, Chirico E, Lermusiaux P, Chambion-Diaz M, Faes C, Boreau A, Chazaud B, Millon A, Pialoux V.

Antioxidants (Basel) 2022 Aug 5;11(8):1529

Viruses in neurodegenerative diseases: More than just suspects in crimes.

P. Leblanc, I. M. Vorberg

PLOS PATHOGENS August 2022 https://doi.org/10.1371/journal.ppat.1010670

Severe congenital myasthenic syndromes caused by agrin mutations affecting secretion by motoneurons.

A. Jacquier · V. Risson · T. Simonet · F. Roussange · N. Lacoste · S. Ribault · J. Carras · J. Theuriet · E. Girard · I. Grosjean · L. Le Goff · S. Kröger · J. Meltoranta · S. Bauché · D. Sternberg · E. Fournier· A. Kostera-Pruszczyk ·
E. O’Connor · B. Eymard · H. Lochmüller · C. Martinat · L. Schaeffer.

Acta Neuropathologica 2022 Aug 10.doi: 10.1007/s00401-022-02475-8.

Expanding the phenotypic variability of MORC2 gene mutations: From Charcot‐Marie‐Tooth disease to late‐onsetpure motor neuropathy.

A. Jacquier, S. Ribault, M. Mendes, N. Lacoste, V. Risson, J. Carras, P. Latour, A. Nadaj-Pakleza, T. Stojkovic, L. Schaeffer

Human Mutation 29 July 2022 https://doi.org/10.1002/humu.24445

DCs unchained: Whetting dendritic-cell appetite boosts wound healing.

Juban G, Chazaud B

Immunity 2022 Jul 12;55(7):1156-1158

XAB2 dynamics during DNA damage-dependent transcription inhibition.

Donnio LM, Cerutti E, Magnani C, Neuillet D, Mari PO, Giglia-Mari G.

Elife 2022 Jul 26;11:e77094. doi: 10.7554/eLife.77094

A stable XPG protein is required for proper ribosome biogenesis: Insights on the phenotype of combinate Xeroderma Pigmentosum/Cockayne Syndrome patients.

Taupelet F, Donnio LM, Magnani C, Mari PO, Giglia-Mari G.

PLoS One 2022 Jul 8;17(7):e0271246. doi: 10.1371/journal.pone.0271246.

Simple Methods for Permanent or Transient Denervation in Mouse Sciatic Nerve Injury Models.

Osseni A, Thomas J-L, Ghasemizadeh A, Schaeffer L, Gache V.

Front. Bio-protocol , 20 June 2022 | doi:10.7554/eLife.70490

Microrchidia CW-Type Zinc Finger 2, a Chromatin Modifier in a Spectrum of Peripheral Neuropathies.

Jacquier A, Roubille S, Lomonte P and Schaeffer L.

Front. Cell. Neurosci. , 03 June 2022 | https://doi.org/10.3389/fncel.2022.896854

Epigenetic Control of Muscle Stem Cells: Focus on Histone Lysine Demethylases.

Cicciarello D, Schaeffer L and Scionti I.

Front. Cell Dev. Biol. 20 May 2022 | doi:10.3389/fcell.2022.917771

Sex differences in semitendinosus muscle fiber-type composition.

Fournier G, Bernard C, Cievet-Bonfils M, Kenney R, Pingon M, Sappey-Marinier E, Chazaud B, Gondin J, Servien E.

Scand J Med Sci Sports. 2022 Apr;32(4):720-727. doi: 10.1111/sms.14127.

Involvement of Type-I Interferon Signaling in Muscle Stem Cell Proliferation During Dermatomyositis.

Gallay L, Fermon C, Lessard L, Weiss-Gayet M, Viel S, Streichenberger N, Corpet A, Mounier R, Gitiaux C, Mouchiroud G, Chazaud B..

Neurology. 2022 Mar 29:10.1212/WNL.0000000000200271.

Hypothalamic-pituitary-adrenal axis activation and glucocorticoid-responsive gene expression in skeletal muscle and liver of Apc mice.

Martin A, Castells J, Allibert V, Emerit A, Zolotoff C, Cardot-Ruffino V, Gallot YS, Vernus B, Chauvet V, Bartholin L, Schaeffer L, Durieux AC, Hourdé C, Favier FB, Mazelin L, Freyssenet D.

J Cachexia Sarcopenia Muscle. 2022 Mar 11. doi: 10.1002/jcsm.12939.

Glucocorticoids coordinate macrophage metabolism through the regulation of the tricarboxylic acid cycle

Stifel U, Wolfschmitt EM, Vogt J, Wachter U, Vettorazzi S, Tews D, Hogg M, Zink F, Koll NM, Winning S, Mounier R, Chazaud B, Radermacher P, Fischer-Posovszky P, Caratti G, Tuckermann J.

Mol Metab. 2022 Mar;57:101424. doi: 10.1016/j.molmet.2021.101424.

Effectiveness of an individualized home-based physical activity program in surgery-free non-endarterectomized asymptomatic stroke patients: a study protocol for the PACAPh interventional randomized trial.

Mura M, Rivoire E, Dehina-Khenniche L, Weiss-Gayet M, Chazaud B, Faes C, Connes P, Long A, Rytz CL, Mury P, Delrieu L, Gouraud E, Bordet M, Della Schiava N, Lermusiaux P, Arsicot M, Millon A, Pialoux V.

Trials. 2022 Feb 14;23(1):145. doi: 10.1186/s13063-022-06061-x.

Immunometabolism-fit: How exercise and training can modify T cell and macrophage metabolism in health and disease.

Rosa-Neto JC, Lira FS, Little JP, Landells G, Islam H, Chazaud B, Pyne DB, Teixeira AM, Batatinha H, Moura Antunes B, Guerra Minuzzi L, Palmowski J, Simpson RJ, Krüger K.

Exerc Immunol Rev. 2022 28:29-46