Institut NeuroMyoGène
    Laboratoire Physiopathologie et Génétique du Neurone et du Muscle
    CNRS UMR 5261 -INSERM U1315
    Université de Lyon - Université Claude Bernard Lyon 1
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We are pleased to welcome Gabrielle KARDON from the Department of Human Genetics in University of UTAH, on June 3rd , invited by Julien GONDIN.
She will give a seminar at 11:30 am entitled: “Muscle Damage and Regeneration after Sterile and Pathogenic Injury”

📍The seminar will be in the Amphi 3, 3rd floor.

 

Abstract

Ross River (RRV) and Chikungunya (CHIKV) viruses are emerging pathogens that target the musculoskeletal system and a major health concern as they cause explosive outbreaks in humans. A major unknown in our understanding of RRV and CHIKV disease is how viral infection causes acute and chronic myalgia and myopathy, an important consequence of viral infection found in 90% of patients. I will present our recent research on how these viruses target and damage muscle and compare how muscle repairs after pathogenic versus sterile injury.

 

Majors publications:

Collins BC, Shapiro JB, Scheib MM, Musci RV, Verma M, Kardon G. (2024). Three-dimensional imaging studies in mice identify cellular dynamics of muscle regeneration. Developmental Cell Mar 29:S1534-5807(24)00184-9.

Keefe AC, Lawson JA, Flygare SD, Fox ZD, Colasanto MP, Mathew SJ, Yandell M, Kardon G (2015). Muscle stem cells contribute to myofibres in sedentary adult mice. Nat Commun, 6, 7087.

Murphy MM, Lawson JA, Mathew SJ, Hutcheson DA, Kardon G (2011). Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration. Development, 138(17), 3625-37

 

Complete List of Published Work in MyBibliography:

https://www.ncbi.nlm.nih.gov/myncbi/gabrielle.kardon.1/bibliography/public/


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