We are pleased to welcome Stéphanie PORTET from the Department of Mathematics in University of Manitoba, Canada on February 27th who is invited by Pascale BOMONT.
He will give a seminar at 11am entitled: “ Transport of intermediate filaments in cells ”.
The seminar will be in the Amphi Hermann, 1st floor.
Abstract
Intermediate filaments are key components of the cytoskeleton, playing essential roles in cell mechanics, signaling, and migration. Their organization into networks is a major determinant of their cellular functions. The spatiotemporal organization of intermediate filaments arises from the interplay between assembly and disassembly processes and various modes of intracellular transport. This presentation will provide an overview of mathematical models used to investigate the effects of different intracellular transport mechanisms on intermediate filament organization.
Major publications:
Research Papers & Reviews
Dallon et al. Stochastic modeling reveals how motor protein and filament properties affect intermediate filament transport. Journal of Theoretical Biology 464: 132-148 (2019).
Dallon et al. Using Fluorescence Recovery After Photobleaching data to uncover filament dynamics. PLoS Computational Biology 18 (2022).
Dallon et al. Steady State Distributions of Moving Particles in One Dimension: With an Eye Towards Axonal Transport. Journal of Mathematical Biology, 89: 56 (2024).
Park et al. Models of vimentin organization under actin-driven transport. Physical Review E, 107:054408 (2023).
Portet et al. Keratin dynamics: modeling the interplay between turnover and transport. PLoS ONE, 10: e121090 (2015).
Portet et al. Deciphering the transport of elastic filaments by antagonistic motor proteins. Physical Review E, 99: 042414 (2019).
Portet et al. Impact of noise on the regulation of intracellular transport of intermediate filaments. Journal of Theoretical Biology. 111183 (2022).